DeSantis isn't going to be picked as Trump's VP candidate. He'll pick whomever his advisors tell him will give him the best chance to win, that's what he did last time and that's what he'll do now. Y'all think he picked Mike Pence because he looked him? He needed Pence for the evangelicals because at the time, that was viewed as a weakness for Trump. He lost some primaries and caucuses because some of the voting base thought of him as too amoral. The republican strategists took for granted just how hypocritical evangelicals can be.
I think he'll likely pick a woman or minority, someone like Sarah Huckabee Sanders, Kim Reynolds, Kelly Ayotte, Elise Stefanik, Kristi Norm, or Uncle Tim Scott.