I know my butthole puckered when we killed Soleimani in Iraq, because (a) Iran, next-door neighbor, actually has a real military with advanced weapons, and (b) we had bases and troops on the ground in Iraq. In fact, Iran did bombard one of our bases, and the reports from troops on the ground are harrowing. Though thankfully, we had enough advance notice that no troops were killed.
By the way, we used the same "flying Ginsu" (<-- elite insider lingo) on Soleimani as we used against Al-Zawahiri.