I had something like that going on in an elbow several yrs ago. Went to the doc, he wanted to operate. Went to PT instead and it turned out to be a nerve issue. Never was a huge amt of pain, just loss of strength with a little pain. Was more annoying than anything, but never took care of itself. Few weeks of PT did the trick.
Being a wrist, it may be due to something you are doing repeatedly regarding keyboard, mouse, or something. Could also be arthritis, though.