Ok. I guess I'll start with The Liar. She wins, meaning the GOP loses the Senate, too.
The Liar's Department of Justice refuses to prosecute her for mishandling classified information. Numerous career FBI agents resign in protest.
She quickly nominates, and the Senate confirms, a fifth "Living Constitution" liberal to the Supreme Court. The "rule of law" is over, because what a law says no longer matters. All that matters is advancing liberal policy. The Liar quickly proceeds with amnesty by executive order, which the Supreme Court upholds 5-4. Poverty pours into the United States at an unprecedented level, drugs and crime soars, and state and local resources are overwhelmed (more so than they already are).
Likewise, liberal policy on restricting energy consumption in the name of "fighting global warming" proceeds via administrative regulation, unchecked by the courts. Price of electricity (the vast majority of which comes from coal) skyrockets higher than even its current rate of increase. OPEC, realizing that the liberals now have a chokehold on US oil production, reverses its policy of flooding the market, quickly escalating gas prices.
Obamacare continues unabated - requiring greater and greater infusions of tax dollars to keep the insurance companies afloat. As premiums continue to soar and access to doctors continues to diminish, The Liar promises single payer healthcare - Medicaid for all. With her new, stronger majority thanks to executive amnesty, she wins reelection easily in 2020. Taxes on income over $90,000 increase significantly to pay for the new Medicaid. Oddly, access to doctors does not improve, and the quality of healthcare continues to decline.
Thanks to a bevy of new employment regulations - including the requirement that all firings first be approved by the newly minted National Anti-Discrimination Agency - employers are increasingly cautious about hiring. Labor Force Participation rate continues to decline, but good news! - the "unemployment rate" remains around 5-6% because those people aren't looking for work and therefore aren't counted.
The national debt continues to grow by at least $600 billion per year. The GOP house, despite frequent sabre rattling over government shutdowns, continues to ultimately cave on massive omnibus spending bills - at least until 2018 when their House majority is swept away.
The Middle East continues to burn - do your really think it's going to get better? - spreading radical Islamic terrorism around the world.
That's a start at least. I'm obviously not anticipating everything.