I think they are setting Maggie up to be the Mayor at Alexandria. I think the actress is trying to do more movies and probably has shittier availability, so they are writing her into a role they can ignore for episodes at a time if need be. My guess is she and Glenn "settle down" in Alexandria and at some point the rest of the crew heads back out/gets separated.
On the other hand, I think they are due to kill off a main character. Rick, Michonne, and Carl are probably safe.