Minneapolis would be a good city to visit this time of year, within the 8 hour range.
Milwaukee is farther than that, or I'd whole heartedly recommend Milwaukee...I love that place.
Memphis is fun. It's dirty and stuff, but fun. Great food, good zoo (they have Pandas), Music scene.
Eureka Springs is an awesome hipster hiking foodie town. Very pretty nature stuff, and B&B's and crap.