One consideration not yet mentioned is injuries and depth. We've dealt injuries already that has helped us develop some depth and we'll see others. We can't afford to have Nelson or Freeman go down. Losing Campbell, Watts, Murphy or Johnson would hurt badly as well.
Missouri can't lose Daniels and having one of their tight ends out would be a blow.
ku has been very healthy, but why shouldn't they? True, injuries can happen against nobodies (see El's senior year) but it seems to me they pile up in a hard-hitting game that really means something, see last year's Texas game for an example, especially if the follow on other games against quality teams. It's the wear down effect. My guess is they have less depth than MU or K-State and as hoax fans keep reminding us, they're young. You know they don't want to try to win without Reesing, but who sees him making it through the year?
But it's not always the stars but the cluster injuries that really hurt. Two or three injuries to the O-line, D-line of D-backs.
In short, if K-State stays healthy, develops consistency and wins some close games, hell yes.