So, one kinda gap that hasn't really been addressed by the show is about the infection
So, per all zombie films, if you get bitten and survive, you'll slowly become a zombie at some point. Alright i'm on board.
[SPOILERS]
Now, TWD has also established that the infection is also dormant in everyone's system all the time. As demonstrated a few different times, if you die a non-walker death and find yourself retaining a functional central nervous system: you will become the walking dead.
Interesting premise, makes for some good story lines, however this begs the questions: what about being bit causes you to turn? You're already infected, what's the bite doing? If its just the physical agitation, people have been afflicted in the show to similar wounds and not turned (e.g being shot, stabbed, lacerated...)
Theres an awful lot of limbs being hacked off in this show for it not even to be discussed.