best business budget brand - Hilton Garden Inn (free business center, free breakfast for hilton golds, easy in and out)
best business regular brand - Embassy Suites (usually will cost a bit more than the local Hilton Garden Inn but the managers reception and free breakfast for all customers are nice. Also enjoy all the extra room and the fact that they are usually right next to the convention center of wherever you are)
best vacation brand - Westin (always seem to have good locations and usually have trendy bars/restaurants. usually a convenience store type place in house and most have pretty great pool bars)
best higher end vacation brand - Hyatt (pretty much all the same things I said about Westin but a little nicer and a little more expensive. I usually go with a Westin if both are available unless I can get into a Hyatt at roughly the same price)
best award miles/points program - SPG (rick daris and I have gone over this a lot in the credit card thread but they have by far the easiest to use program with tons of options for using points)
best status program - HH (hilton will give you free breakfasts, upgrades to club floor and additional mileage just for reaching gold status. You can get extra mileage with other programs but you usually won't sniff club lounge access until you reach their highest tier. I can't even get a room upgrade as a Hyatt Platinum which is above their gold tier. All they offer is the best available room in my category booked.)