Personally, I like the fact that Notre Dame, a good but lucky team, is going on the road to face a very talented team (with a young, confident quarterback) that has nothing to lose and is acting like it.
There also isn't much film on this kid for Notre Dame to get their hands on.
My guess? USC comes out and puts it all out there to wreck their season.
I honestly think ND loses this game by 10+.