Rainey street might be your jam, then. No breweries (as far as I know), but tons of bars and restaurants. There is (was?) a craft beer garden on the south end that serves a lot of local beers. In terms of breweries in Austin, they tend to be pretty far flung and not close to other attractions. Sounds like you've got the music thing covered, so I won't give you recs on that.
The other concentrations of food/booze/entertainment would be E. 6th street ("Dirty Sixth," sloppy college kids; don't recommend), W. 6th (slightly older, douchier crowd; feels like Dallas), S. Congress ("SoCo," hip/trendy), S. Lamar ("SoLa," mix of good restaurants, bars, and music, but kinda spread out), and the Domain (a sprawling outdoor complex of stores, restaurants, bars, and other stuff like Top Golf).
If you really want a destination spot, Jester King brewery is SW of town. Maybe a 45 minute drive. But worth it.