The comparison isn't between no one OD'ing and people OD'ing from a legal substance. The comparison is how much death and destroyed lives we can prevent by decriminalization, regulated markets, and treatment for addicts.
We already have a ton of ODs because people don't know what they are taking and we have a ton of deaths and destroyed lives from the drug war. Several people on this board think we can do better, you seem content with the status quo. That's fine, but you should look at what that actually is.