Here are a couple of food places I would recommend. For pizza, you might try Lou Malnati's. There are a bunch of pizza places but I like this one the best for deep dish. The River North location (if you're downtown, it's the closest) is on about the 400 block of Wells street. There are other locations that I am sure you can find on the web. For good fast food, find a Portillo's. You have tons of choices. The downtown location is at about the 100 block of West Ontario. If you want to be ridiculed by out-of-work or part-time actors go to Ed Debevic's. It's a pretty fun place on Ontario (I think). If you want to see the place that Saturday Night Live made famous, go to lower Michigan Ave (near the Tribune building by the river, under the Mag Mile, you take stairs down to the lower sets of roads – it's cool just to go down there and see the underside of the city) and try out the Billy Goat Tavern.
Speaking of Ontario, if you want to do touristy stuff, you can go to about Clark and Ontario (I think) and there are all the places every city has, Hard Rock, Planet Hollywood, etc. You might also head over to the museum campus. The Science and Industry Museum (south of the campus quite a ways) and the Field Museum are great places if you like that stuff. The Shedd aquarium is right there, the Art Museum (a little north of the campus), etc. There is a good ancient history museum that most people don't know about, the Oriental Institute near the U. of C. This is on the near south side close to the Museum of Science and Industry.
For other music, the Blues are a Chicago favorite. You could check out Kingston Mines (about the 24-2500 block of N. Halstead), Buddy Guy's Legends (somewhere on Wabash, maybe the 500-800 block south), or the House of Blues (it's the most touristy of these three but has some cool stuff to see) on N. Dearborn somewhere (500 block?).
I'm leaving for Denver this morning and won't be on the board for awhile. I hope this helps. Have a great time in Chicago.